Statins: the business of the 21st century

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One out of four american citizens is taking statins. The “experts” recommend them to more and more people each year.

So, what are statins?

Statins are drugs that block the enzyme that produces cholesterol, the (HMG-CoA reductase)

The fact that statins have side effects has been proved by almost nine hundred studies. Amongst their side effects one can find muscular and cognitive problems. There are of course many more like anaemia, erectile dysfunction, immunosuppression or even cataracts.

All of these side effects seem less dangerous when we talk about the biggest one: Statins raise insulin resistance. If you´ve read the last post, you´ll know that people who use statins usually do it for some cardiovascular problem. Moreover, most of those people already have high insulin resistance. Do you see where the problem is?

The statins will raise their insulin resistance and their doctor will diagnose them with type 2 diabetes… Result: medication for the diabetes too…

They´ll be medicated for two conditions they don´t have… incredible but true. The famous JUPITER study, conducted a few years ago that supposedly showed how statins drop the risk of heart disease was sponsored by the statins industry and is nowadays discredited.

 

We should take into account that cholesterol isn´t the culprit of heart disease and the small, (if any) ability of statins to reduce the risk of heart disease (as the JUPITER study says, less than 2% of absolute reduction of risk) Knowing that, these drugs should be given only to people with a history of adverse cardiovascular events, never as a preventive treatment for people with high levels of serum cholesterol as unique indicator.

Out of 100 people who take this drug only 2 enjoy the benefits and more than 25 have to deal with serious side effects.

Isn´t it scandalous?

The most well-known statins are Pravachol, Lipitor, Zocor, Crestor and Mevacor but there are many more available as generic drugs, which are cheaper.

Knowing that the statins industry made 34 billion dollars in 2008, everybody will understand the connection.

As we already said in the last post, if you want to know your risk of developing heart disease, you can take a look at the following graph and measure both your total cholesterol/HDL ratio and your triglycerides/HDL ratio. If you fit in the left column, there’s nothing to be worried about.

Resultado de imagen de hdl/total cholesterol

 

Summary:

-There’s a 2% chance that you’ll benefit from taking statins.

-There’s a 50% chance that you’ll experiment side effects when taking statins.

-If you’re taking drugs for both cholesterol and type 2 diabetes you may not have any of these conditions.




References:

http://www.nejm.org/doi/pdf/10.1056/NEJM198807073190105

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411536/https://www.ncbi.nlm.nih.gov/pmc/?term=side+effects+statins

http://www.nejm.org/doi/full/10.1056/NEJMoa0807646#t=articlehttp://www.forbes.com/forbes/welcome/?toURL=

http://www.forbes.com/2008/10/29/cholesterol-pharmacuticals-statins-biz-cx_mh_1030cholesterol.html&refURL=

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